Posts Tagged receptor antagonists
Vision Shopsters: Alzheimers Disease: Drug Treatment Strategies 2010
This report presents the findings of a comprehensive survey of current clinical practices in the treatment of Alzheimer’s Disease (AD). This was carried out following the participation of more than 220 physicians, practicing predominantly in the US. The purpose of this study was to establish current everyday drug treatment practices for AD and how current drug classes, individually and in combination, are prescribed for mild, moderate and severe stages of the disease. As part of this survey, more than 200 physicians also reported on the principal challenges of treating this disease and these findings are presented, analysed and discussed in this report.
The treatment of AD remains an area of significant unmet need, with therapies based largely on two drug classes: the cholinesterase inhibitors and the NMDA receptor antagonists. These drugs target the symptoms of the disease, however there is considerable need for disease-modifying therapies. Other therapeutic agents are used to treat this disease, which have also been surveyed as part of this work. This survey investigated the use of these drug classes for the treatment of mild, moderate and severe AD, as well as examining the use of drug combinations. While available drugs to treat AD are limited, current practices in how they are used and combined in treating mild, moderate and severe disease, vary greatly. This survey has examined current treatment practices, which includes off-label use.
Topic: cholinesterase inhibitors, clinical practices, drug combinations, drug treatment strategies, nmda receptor, principal challenges, receptor antagonists, therapeutic agents, therapeutic field, treatment practicesRelated Topic
Prostate Cancer – Germany Drug Forecasts and Treatment Analysis to 2020
GlobalData analysis finds that the prostate cancer therapeutics market in Germany is attractive and is primarily driven by the growth in the hormone-refractory prostate cancer therapeutics market. The growth in the number of total patients receiving treatment and increase in the annual cost of hormone-refractory prostate cancer therapy is expected to offset the impact of generic erosion in hormone-dependent prostate cancer therapy. The patient volume was driven by growth in treatment usage patterns such as diseased population, treatment seeking population, diagnosis population and prescription population. The annual cost of prostate cancer therapy between 2001 and 2009 was driven by increased uptake of chemotherapy using Taxotere. Expected launch of new therapies such as Provenge (sipuleucel-T) and Jevtana (cabazitaxel) will further drive the annual cost of therapy.
Hormone therapy using combination of hormone therapies such as LHRH agonists and androgen receptor antagonists is a prominent treatment regime. Taxotere is the current standard of care for patients that stop responding to hormone therapy. The introduction of new therapies for metastatic prostate cancer is expected to expand the market further.
Topic: androgen receptor, cancer therapeutics, casodex bicalutamide, hormone refractory prostate cancer, hormone therapies, prostate cancer, prostate cancer therapy, receptor antagonists, refractory prostate cancer, treatment regimeRelated Topic